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Single agent, canfosfamide (C, TLK286) vs pegylated liposomal doxorubicin (D) or topotecan (T) in 3rd-line treatment of platinum (P) refractory or resistant ovarian cancer (OC): phase 3 study results [Abstract]

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generally avoided Concurrent use with other potent neuroactive compounds: manage carefully Recommended precautions Always begin under physician supervision with a full medical history review Start at the lowest effective dose and titrate slowly Use cycling protocols avoid indefinite continuous use Monitor for neurological overstimulation symptoms Regular follow-up consultations during active protocols Who may be a candidate for Dihexa therapy